Apparatus and methods for monitoring the status of a metabolically active cell , et al., Patent #7,704,745 B2, issued 27 Apr. 2010.

Abstract:

An apparatus and methods for monitoring the status of a cell that consumes oxygen. In one embodiment of the present invention, the method includes the steps of confining the cell in a sensing volume, measuring dynamically intracellular or extracellular signaling of the cell, and determining the status of the cell from the measured intracellular or extracellular signaling of the cell.


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